The mental state disorder and moods of people play to increase their weight, as many studies have shown a close relationship between poor mental state and obesity.
The most important psychological causes that cause weight gain:
Here are some of the reasons for mental disorders, which are considered one of the factors that lead to weight gain, the most important of which are:
1) Depression and psychological stress:
Depression is one of the factors that cause weight gain, due to the desire of some people to eat large quantities of food due to their poor health, as well as lack of movement and activity, which makes them resort to excessive intake of foods, especially rich in sugars.
2) mental obsession:
Patients suffering from some psychological disorders such as mental obsession opens the patient's appetite for food, and the patient then becomes unaware of the quantity and type of food he is eating.
3) Psychiatric Medicines:
Most psychiatric drugs are one of the factors that cause weight gain, such as drugs for mental disorders, the most famous of which are schizophrenia and depression.
The medications, which incorporate clozapine, olanzapine, ziprasidone and numerous others, "fill a significant need," said Dr. Zachary Freyberg, the senior analyst on the new investigation.
"Much of the time," he added, "they can be life-saving."
The problem is their "metabolic" side effects, said Freyberg, an assistant professor of psychiatry and cell biology at the University of Pittsburgh School of Medicine.
Antipsychotics often trigger weight gain, cholesterol spikes and elevations in blood sugar that can lead to type 2 diabetes.
In fact, those side effects commonly drive patients to stop taking the drugs, said Dr. Ken Duckworth, chief medical officer of the nonprofit National Alliance on Mental Illness.
Duckworth, who was not associated with the new examination, said it's essential to comprehend why those antagonistic impacts happen.
These discoveries, he said, "start to disentangle" the issue.
In particular, the Pitt specialists focused in on dopamine, a synthetic that sends messages between cells by interfacing with receptors on their surfaces. In the mind, dopamine assumes a part in delight, inspiration and learning.
While there are numerous antipsychotic drugs, they all work likewise: hindering certain dopamine receptors, known as D2-like receptors.
On the off chance that those receptors just existed in the mind, that may be great.
As a general rule, Freyberg clarified, the body really has more dopamine receptors outside the mind than inside it.
"It's innocent to think [antipsychotics] just work from the neck up," he said.
Basically, there are D2-like receptors on cells in the pancreas, as well. Certain pancreatic cells produce chemicals that either raise glucose (glucagon) or lower it (insulin).
In lab tries different things with pancreatic cells, Freyberg's group found that dopamine affected the creation of both glucagon and insulin. Also, the actual cells were really equipped for producing their own dopamine, affirming the significance of the synthetic external the cerebrum, the examination creators said.
At that point, when the analysts utilized antipsychotic meds to impede the pancreatic cells' D2-like receptors, that inclined up the creation of both glucagon and insulin.
In the body, unchecked arrival of those chemicals could rapidly prompt a misfortune in insulin affectability and persistently high glucose levels.
The uplifting news, Freyberg said, is that understanding the "why" may now permit specialists to create antipsychotic meds that deflect metabolic results.
"This makes it all to a lesser degree a discovery," Duckworth said.
Also, scientists are dealing with meds that don't target dopamine by any means. A year ago, an early preliminary found that a trial prescription, named SEP-363856, facilitated a variety of indications in individuals with schizophrenia. They included visualizations and hallucinations, however issues like straightened feelings and social withdrawal.
The medication lets D2-as be receptors.
The takeaway, both Duckworth and Freyberg said, is that patients' challenges with current antipsychotics are being heard.
"Researchers are chipping away at this," Duckworth said.
For the present, the test for patients is to deal with the results all that can be expected. The initial step is staying alert that they can occur, Duckworth noted, since individuals being recently recommended an antipsychotic are not really ready to handle all the data they're getting.
As far as possible weight acquire, numerous individuals need to change the manner in which they eat, Duckworth said, exchanging "family-style" eating for parcel control.
Actual work is additionally key. Duckworth proposed individuals attempt to make practice an approach to associate socially too, by going to the neighborhood Y, for example.
As far as it matters for them, Duckworth said, specialists ought to screen patients' weight, glucose and cholesterol, to get undesirable changes.
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